B.S. Bioengineering University of Illinois-Urbana-Champaign 2002
Ph.D. Physiology Southern Illinois University-Carbondale 2007
Postdoctoral Training at Washington University-St. Louis 2007-2013
Assistant Research Scientist at University of Iowa 2013-2016
Assistant Professor 2016-present
Dr. Wiley has been an Assistant Professor at the Stephen A. Wynn Institute for Vison Research since February 2016.
Previously, Dr. Wiley worked as an Assistant Research Scientist under Dr. Tucker in the Tucker Stem Cell Lab (TSCL). While in the TSCL, his work focused on using induced pluripotent stem cells (iPSCs) to model and treat retinal degenerative diseases. Dr. Wiley continues to be a close collaborator in the TSCL working on the development of gene therapy vectors to treat various inherited retinal diseases.
As PI of the Wiley Lab, Luke is continuing his interests in using patient-specific iPSCs to develop high-throughput drug screening methods to identify potential pharmacological agents to treat CLN3 Batten disease and using cells from patients with NR2E3-associated retinal disease to learn about retinal cell development and differentiation. The Wiley Lab is also focused on using iPSCs to generate patient-specific corneal endothelial cells and limbal stem cells to investigate and treat Fuchs endothelial corneal dystrophy and limbal stem cell deficiency in the cornea.