Construction Completed on Steven W. Dezii Translational Vision Research Facility

Tue, 07/01/2014 - 14:00

The recently dedicated Steven W. Dezii Translational Vision Research Facility located within the Wynn Institute for Vision Research is a state-of-the-art ISO Class 5/6 biomedical human research good manufacturing practice (GMP) laboratory. This facility contains an equipment room with a -85C freezer, a -30C freezer, and 1 2-8C refrigerator. There are 2 ISO Class 6 air showers with PPE gowning areas and 2 ISO Class 5 processing rooms equipped with 2 BioSpherix Isolation units and 2 centrifuges. One processing room also has a GE Healthcare ion exchange chromatography AKTA virus purification system for the purification of clinical grade viral particles. This GMP facility will be used for the culture of xeno-free patient-specific iPSC cell lines for future human transplantation trials, as well as the clean and expedited production of our own in-house adeno-associated viral and lentiviral particles for use in human gene augmentation and gene replacement trials.